Early Detection of Pancreatic Cancer: Why Surgery Offers the Best Chance of Cure

Pancreatic cancer is not very common in India, but it is one of the deadliest cancers because it is often detected late. The pancreas sits deep inside the abdomen, so early tumours usually cause no clear symptoms. When detected early, surgery can remove the tumour completely — and this is the only potential cure for pancreatic cancer.

Pancreatic Cancer in India

According to GLOBOCAN estimates, India sees a few thousand new cases each year, and numbers are slowly rising. Even with lower incidence, late diagnosis makes pancreatic cancer a major cause of cancer-related deaths.

Why Early Detection Matters

Only 15–20% of patients are diagnosed early enough for surgery.
When the tumour is removed completely and followed by chemotherapy:

  • Cure becomes possible
  • Long-term survival rises to 15–25%
  • Outcomes are best in very early-stage cancers

Warning Signs You Should Not Ignore

If these symptoms last more than a few weeks, consult a doctor:

  • Persistent upper abdominal or back pain
  • Unexplained weight loss
  • Painless jaundice
  • New-onset diabetes after age 50
  • Pale, greasy stools or persistent nausea

These symptoms are not always cancer — but they should be checked early.

Who Needs Extra Attention?

You may need closer monitoring if you have:

  • A family history of pancreatic cancer
  • Genetic conditions (BRCA, PALB2, Peutz–Jeghers)
  • Long-standing chronic pancreatitis
  • Smoking history
  • Sudden onset diabetes in older age

High-risk individuals may undergo MRI/MRCP or EUS surveillance at specialist centres.

How Doctors Detect It Early

  • Blood tests including CA 19-9
  • CT scan, MRI, or Endoscopic Ultrasound
  • Biopsy if needed
    A multidisciplinary team decides the best plan for each patient.

Surgery: The Only Curative Option

Surgery removes the tumour entirely and offers the highest chance of cure.

Main Surgeries Used

  • Whipple Procedure: For tumours in the pancreas head
  • Distal Pancreatectomy: For body/tail tumours
  • Total Pancreatectomy: Rarely used; requires lifelong insulin
  • Vascular Reconstruction: Allows more patients to become operable at advanced centres

Minimally invasive (laparoscopic/robotic) options are available in selected cases.

Other Treatments That Support Surgery

  • Adjuvant Chemotherapy: Given after surgery (e.g., modified FOLFIRINOX) to reduce recurrence
  • Neoadjuvant Therapy: Before surgery to shrink borderline tumours
  • Advanced Disease Treatment: Modern chemotherapy, targeted therapy (for selected gene mutations), and immunotherapy
  • Radiation & Palliative Care: For symptom control and improved quality of life

Healius Takeaway

At Healius, we believe early detection saves lives. Knowing the warning signs, acting quickly, and choosing specialised pancreatic centres gives patients the strongest chance for cure. If surgery is possible, it changes everything.

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