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Targeted Therapies & Immunotherapy: The Future of Blood Cancer Care

Blood cancer is one of the most challenging cancers, but recent breakthroughs in targeted therapies and immunotherapy are changing the way patients are treated. These advanced approaches not only improve survival rates but also reduce side effects compared to traditional chemotherapy. At Healius Cancer & Hematology Clinics, we are committed to bringing world-class cancer care closer to patients, making us one of the most trusted blood cancer treatment centers in Bangalore. Understanding Blood Cancer and Its Symptoms Blood cancers like leukemia, lymphoma, and myeloma affect the blood, bone marrow, or lymphatic system. Early detection makes a significant difference. Common blood cancer symptoms in Bangalore patients include: How Targeted Therapies Work Unlike chemotherapy, which attacks both healthy and cancerous cells, targeted therapies focus only on the specific cancer-causing genes, proteins, or tissues. This makes treatment more effective and reduces side effects. At Healius, our oncology team uses advanced molecular diagnostics to determine whether targeted therapy is suitable for each patient, ensuring a personalized approach to care. Immunotherapy – Harnessing the Power of the Immune System Immunotherapy activates the body’s own immune system to fight cancer cells. One of the most promising advances is CAR-T cell therapy in Bangalore, where a patient’s T-cells are engineered to better recognize and destroy cancer cells. This breakthrough is especially effective in certain types of leukemia and lymphoma. Specialized Care for Lymphoma and Bone Marrow Transplants At Healius, our lymphoma specialists in Bangalore provide expert guidance on treatment options tailored to each patient’s needs. For advanced cases, we also offer bone marrow transplant in Bangalore, a life-saving procedure that replaces diseased marrow with healthy stem cells, offering hope for long-term remission. Why Choose Healius? Final Thoughts The future of blood cancer care lies in precision medicine – and targeted therapies and immunotherapy are at the heart of this transformation. At Healius Cancer & Hematology Clinics, we are dedicated to providing patients with the latest treatment innovations, compassionate care, and hope for tomorrow. If you or a loved one is experiencing blood cancer symptoms in Bangalore, don’t wait. Book an appointment with our experts at Healius Cancer & Hematology Clinics today and consult with the best hematologists in Bangalore for world-class treatment. Contact: +91 9900613143 Location: banashankari, 2nd stage

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Ovarian Cancer Treatment in Bangalore | Healius Cancer & Hematology Clinics

Why Ovarian Cancer is Called the ‘Silent Killer’

Ovarian cancer is often referred to as the “silent killer” because it usually develops without obvious warning signs in its early stages. By the time symptoms become noticeable, the disease is often advanced, making treatment more challenging. At Healius Cancer & Hematology Clinics, we are committed to raising awareness, improving early detection, and providing world-class treatment options, making us one of the best ovarian cancer hospitals in Bangalore. Why Early Symptoms Are Overlooked Ovarian cancer often presents with vague and non-specific symptoms such as: These signs are often mistaken for digestive or urinary issues, which delays diagnosis. This is why awareness and preventive screenings are so crucial. The Importance of Early Detection Unlike other cancers, there is no reliable routine screening test for ovarian cancer. Regular checkups with specialized ovarian cancer doctors in Bangalore are essential, especially for women with family history or genetic risk factors (like BRCA mutations). Early detection significantly improves treatment outcomes and survival rates. Advanced Treatment Options at Healius At Healius, we bring together advanced technology and experienced specialists to provide comprehensive ovarian cancer care: 1. Robotic Surgery for Ovarian Cancer Minimally invasive robotic surgery for ovarian cancer in Bangalore allows greater precision, less blood loss, faster recovery, and smaller scars compared to traditional surgery. This cutting-edge technique ensures patients have access to the best surgical outcomes. 2. Chemotherapy for Ovarian Cancer Chemotherapy for ovarian cancer remains a cornerstone of treatment, targeting cancer cells throughout the body. At Healius, patients receive personalized chemotherapy plans under close monitoring to minimize side effects and maximize effectiveness. 3. Multidisciplinary Care Our team of oncologists, hematologists, and surgeons work together to design individualized treatment plans. This holistic approach ensures that every patient receives not just treatment, but also emotional and nutritional support throughout their journey. Why Choose Healius? Final Thoughts Ovarian cancer may be called the “silent killer,” but with increased awareness, timely consultation, and advanced treatment options, it doesn’t have to remain silent anymore. At Healius Cancer & Hematology Clinics, we stand by women at every stage — from early detection to recovery — ensuring compassionate care backed by the latest medical innovations. If you or a loved one is experiencing persistent symptoms, consult the expert ovarian cancer doctors in Bangalore at Healius Cancer & Hematology Clinics today. Early action saves lives. Book an appointment: +91 9900613143 Location: Banashankari 2nd stage, Bangalore 560070

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Leukemia & Lymphoma in Children vs. Adults: What You Need to Know

Leukemia & Lymphoma in Children vs. Adults: What You Need to Know Leukemia and lymphoma are two of the most common types of blood cancers. While they can occur at any age, the way these diseases present and progress in children vs. adults often differs. Understanding these differences is key to early detection and effective treatment. At Healius Cancer & Hematology Clinics, Bangalore, we provide comprehensive care including blood cancer treatment in Bangalore, chemotherapy at economical cost, and radiation therapy in Bangalore to support patients at every stage of their journey. Causes & Risk Factors Though the exact causes of leukemia and lymphoma are not always known, several risk factors have been identified: Genetic predisposition – Family history of blood cancers increases the risk. Weakened immune system – Conditions like HIV or immune-suppressing treatments may lead to higher vulnerability. Environmental exposure – Prolonged exposure to radiation or harmful chemicals can trigger changes in blood cells. Age-related factors – Certain leukemias are more common in children (like acute lymphoblastic leukemia), while others are seen more in adults (like chronic lymphocytic leukemia). Symptoms to Watch For The symptoms may vary in children and adults, but some common warning signs include: Persistent fatigue and weakness – Low red blood cells cause anemia and constant tiredness. Unexplained fever and frequent infections – A weak immune system leads to repeated illness. Swollen lymph nodes or abdomen – Enlarged nodes or spleen can indicate lymphoma or leukemia progression. Easy bruising or bleeding – Platelet deficiency causes nosebleeds, gum bleeding, or unusual bruises.  If you notice these symptoms in yourself or your child, seek specialized hematology consultation in Bangalore immediately. Treatment Options at Healius At Healius Cancer & Hematology Clinics, we offer advanced yet affordable treatments tailored for both children and adults: Chemotherapy at economical cost – Targeted medications to destroy cancer cells while minimizing side effects. Radiation therapy in Bangalore – Advanced technology to treat lymphomas effectively and safely. Immunotherapy & Targeted Therapy – Modern approaches to boost the immune system and attack only cancerous cells. Bone Marrow Transplant referrals & support – For cases where intensive treatment is required. Why Choose Healius? Expert Oncologists & Hematologists led by Dr. Mangesh Kamath with vast experience in blood cancer treatment. Affordable care with chemotherapy at economical cost and accessible treatment plans. Personalized approach for children and adults with age-specific treatment protocols. Comprehensive support including nutrition counseling, rehabilitation, and caregiver guidance. At Healius, we combine compassionate care with world-class medical expertise to give patients the best chance of recovery. Contact Us – Begin the Journey of Healing  Location: Healius Cancer & Hematology Clinics, Banashankari 2nd stage, BangaloreContact: +91 9900613143  Website: www.healiuscancerhematology.com If you or your loved one is looking for blood cancer treatment in Bangalore, trust Healius for advanced care, affordable treatment options, and expert guidance. Conclusion  Early detection and timely treatment save lives. This Leukemia & Lymphoma Awareness Month, let’s spread awareness and give hope to those fighting blood cancers. Book an Appointment

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Vaccines and Screening for Women’s Cancers

The word “cancer” often brings fear. But today, we have vaccines that can help prevent some cancers. One of the most important is the HPV vaccine, which protects against human papillomavirus (HPV) – a common sexually transmitted virus. Nearly 50% of sexually active people are exposed to HPV at some point. While most infections go away on their own, some high-risk types can cause cancers of the cervix, vagina, vulva, anus, penis, and even parts of the throat. 📊 Gynaecological Cancers in India – At a Glance 👉 Most of these cancers are detected late, making prevention and early detection very important. Why Vaccination Matters HPV Vaccine – A Proven Shield New Vaccines in Development Types of Vaccines Type Purpose Examples Status Preventive Stops cancer before it starts HPV vaccines (Gardasil, Cervarix, Cervavac) ✅ Approved & available Therapeutic Helps fight existing cancer BRCA1/2, p53, HER2, WT1 vaccines 🔬 In research 💡 “Your Questions, Answered” 💡 Can married women take HPV vaccine? Yes, up to 26 years (sometimes till 45).💡 Will vaccines cure cancer? No, HPV vaccine prevents infection. Others are in trials.💡 Do vaccinated women still need Pap tests? Yes, because not all risks are covered.💡 Are BRCA vaccines available in India? Not yet – only in research. September is Gynaecological Cancer Awareness Month 🌸 At Healius Cancer and Haematology Clinics, you can: ✅ Final NoteGynaecological cancers affect lakhs of women in India every year. The HPV vaccine and regular screening are powerful tools to prevent cervical cancer, while new vaccines offer hope for ovarian and uterine cancers. At Healius Cancer and Haematology Clinics, guided by Dr. Mangesh Kamath, women receive world-class, updated treatment and prevention strategies with a strong focus on patient care and awareness.

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Appendix Cancer Treatment

Appendix Cancer Treatment in Bangalore

Appendix cancer is a rare type of cancer that starts in the appendix, a small pouch attached to the large intestine. While it is uncommon, it can be serious if not detected and treated early. Many patients discover appendix cancer accidentally during surgeries for other conditions, such as appendicitis. At Healius Cancer & Hematology Clinics, Bangalore, under the expertise of Dr. Mangesh Kamath, patients receive accurate diagnosis, advanced treatments, and compassionate care for appendix cancer. This blog will help you understand appendix cancer, its types, symptoms, risk factors, diagnostic procedures, and treatment options available in Bangalore. What is Appendix Cancer? Appendix cancer occurs when abnormal cells grow uncontrollably in the appendix. Depending on the type, it may be slow-growing or aggressive, potentially spreading to other organs. Unlike other gastrointestinal cancers, appendix cancer often has no obvious symptoms in its early stages. Types of Appendix Cancer Symptoms of Appendix Cancer Appendix cancer symptoms often mimic other abdominal problems, making early detection challenging: In many cases, the cancer is discovered unexpectedly during surgery for suspected appendicitis. Causes and Risk Factors While the exact cause is unknown, certain factors may increase the risk: Diagnosis of Appendix Cancer At Healius Cancer & Hematology Clinics, diagnosis involves: Appendix Cancer Treatment in Bangalore Treatment depends on the type, size, and stage of the cancer: 1. Surgery 2. Hyperthermic Intraperitoneal Chemotherapy (HIPEC) 3. Systemic Chemotherapy 4. Targeted Therapy & Immunotherapy Why Choose Healius Cancer & Hematology Clinics, Bangalore? Life After Appendix Cancer Treatment Recovery depends on the stage at which cancer is diagnosed and the type of treatment used. Many patients lead healthy lives post-treatment with proper follow-up and lifestyle adjustments: Conclusion Appendix cancer is rare, but early diagnosis and advanced treatment can significantly improve survival rates. At Healius Cancer & Hematology Clinics, Bangalore, Dr. Mangesh Kamath and his team ensure that patients receive the latest and most effective treatments with a compassionate approach. If you or your loved one is diagnosed with appendix cancer, don’t delay consultation. 📞 Call 9900613143 today to book an appointment with Dr. Mangesh Kamath and begin your journey towards recovery.

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How Breastfeeding Protects Women from Breast Cancer | Dr. Mangesh Kamath – Healius Clinics

How Breastfeeding Protects Women from Breast Cancer

How Breastfeeding Protects Women from Breast Cancer Breast cancer is one of the most common cancers affecting women worldwide. While genetics, age, and lifestyle factors play a significant role in its development, research shows that breastfeeding offers a natural and effective way to reduce the risk. Breastfeeding not only benefits the baby by providing essential nutrition and immunity but also protects the mother’s health in multiple ways. In this article, we’ll explore how breastfeeding acts as a protective shield against breast cancer, backed by medical research, expert opinions, and practical advice from Dr. Mangesh Kamath, Senior Consultant in Medical Oncology, Hemato-Oncology, and Bone Marrow Transplant at Healius Cancer & Hematology Clinics, Bangalore. Understanding Breast Cancer Breast cancer develops when abnormal cells in the breast grow uncontrollably, forming a tumor. These cells can invade surrounding tissues or spread (metastasize) to other parts of the body. Some common risk factors include: While some of these risk factors cannot be changed, lifestyle choices—including breastfeeding—can significantly reduce the likelihood of developing the disease. How Breastfeeding Reduces Breast Cancer Risk 1. Hormonal Changes During Breastfeeding When a woman breastfeeds, her body produces less estrogen and progesterone—hormones that can promote the growth of certain breast cancer cells. Reduced exposure to these hormones lowers the risk of cancer development. 2. Shedding of Breast Tissue During lactation, the breast undergoes changes to produce milk. After breastfeeding ends, the body naturally sheds breast tissue. This process can help eliminate cells with potential DNA damage, reducing the likelihood of them turning cancerous. 3. Delay in Menstrual Cycles Exclusive breastfeeding can delay the return of regular menstrual cycles (lactational amenorrhea). This reduces the total number of menstrual cycles a woman experiences in her lifetime, thus lowering lifetime hormone exposure. 4. Enhanced Differentiation of Breast Cells Breast cells mature and change during pregnancy and breastfeeding, making them more resistant to mutations that can lead to cancer. Scientific Evidence Supporting the Benefits Numerous studies have shown a link between breastfeeding and lower breast cancer risk: How Long Should You Breastfeed for Maximum Benefit? While any duration of breastfeeding provides health benefits, research suggests: Additional Health Benefits of Breastfeeding Breastfeeding’s benefits go beyond breast cancer prevention: Overcoming Common Breastfeeding Challenges Many women face difficulties in breastfeeding, such as: Tips to Overcome Challenges: When to Consult a Doctor While breastfeeding offers protection, it’s not a guarantee against breast cancer. Be alert for warning signs: If you notice any of these, seek prompt medical attention. Expert Advice from Dr. Mangesh Kamath According to Dr. Mangesh Kamath, “Breastfeeding is one of the simplest and most natural steps women can take to lower their breast cancer risk. Even partial breastfeeding can have a positive effect. However, regular breast screenings and a healthy lifestyle remain essential for overall protection.” Lifestyle Tips to Complement Breastfeeding’s Protective Effect Key Takeaways Conclusion Breastfeeding is more than a way to nourish your baby—it’s a powerful, natural strategy for protecting your long-term health. Backed by scientific evidence, it plays a significant role in reducing breast cancer risk. If you have questions about breast health, cancer prevention, or need guidance on breastfeeding challenges, visit Healius Cancer & Hematology Clinics in Bangalore and consult Dr. Mangesh Kamath for personalized care.

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Lung Cancer Treatment in Bangalore | Dr. Mangesh Kamath – Healius Clinics

Lung Cancer Treatment in Bangalore | Dr. Mangesh Kamath – Healius Clinics

Lung cancer is one of the most common cancers worldwide, affecting both men and women. Early detection and effective treatment can significantly improve survival rates. At Healius Cancer & Hematology Clinics, we provide advanced lung cancer care under the expertise of Dr. Mangesh Kamath, one of Bangalore’s leading cancer specialists. What is Lung Cancer?Lung cancer begins in the lungs and can spread to other parts of the body if not treated promptly. It is typically classified into two main types: Causes and Risk Factors Symptoms of Lung Cancer Diagnosis at Healius ClinicsWe use advanced diagnostic tools such as CT scans, PET scans, bronchoscopy, and biopsy to ensure accurate detection. Treatment Options At Healius Cancer & Hematology Clinics, we provide a comprehensive approach including: Why Choose Dr. Mangesh Kamath? Contact Details📞 Call: 9900613143📍 Healius Cancer & Hematology Clinics, Bangalore ConclusionIf you or a loved one is facing lung cancer, early consultation can make all the difference. Get expert, compassionate care from Dr. Mangesh Kamath at Healius Cancer & Hematology Clinics.

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Chronic Lymphocytic Leukaemia (CLL): The Slow but Manageable Blood Cancer

Chronic Lymphocytic Leukaemia (CLL): The Slow but Manageable Blood Cancer 🩸 What is CLL? Chronic Lymphocytic Leukaemia (CLL) is a type of blood and bone marrow cancer where the body makes too many abnormal white blood cells called lymphocytes. These cells look normal but do not work properly to fight infections. Over time, they build up in the blood, bone marrow, and lymph nodes, pushing out the healthy cells. Unlike aggressive leukaemia’s like AML or ALL, CLL is slow-growing. Many people live with CLL for years before needing treatment. In fact, some people may never need active therapy and are only monitored. 🌍 How Common is CLL? ⚠️ Risk Factors and Causes The exact cause of CLL is not known. But certain risk factors make it more likely: 👉 CLL is not contagious and is not caused by lifestyle or diet. 🔍 Common Symptoms of CLL Many patients are diagnosed during a routine blood test without any symptoms. When present, symptoms may include: 🧪 How is CLL Diagnosed? 🎯 Risk Stratification in CLL CLL does not behave the same way in every patient. Some people live for decades without treatment, while others need immediate therapy. Risk stratification helps doctors decide the best approach. 🔹 Risk Stratification Systems in CLL: 👉 These risk groups guide whether a patient should be on watch & wait, given tablets, or considered for advanced therapies. 💊 Treatment Options for CLL 1. Watchful Waiting (Active Surveillance) 2. Targeted Therapy 3. Chemo-Immunotherapy 4. Monoclonal Antibodies 5. Stem Cell Transplant 🚀 Recent Advances in CLL Treatment 📊 CLL vs Other Leukaemias – A Simple Comparison Feature CLL CML ALL AML Progression Slow (chronic) Slow (chronic) Fast (acute) Fast (acute) Typical Age >60 yrs 40–60 yrs Children & young adults Mostly adults, esp. >60 yrs Cells Involved Lymphocytes Myeloid cells Immature lymphoblasts Immature myeloid cells Symptoms Often none early; enlarged nodes, fatigue Fatigue, splenomegaly, high WBC Fever, bleeding, bone pain Fatigue, bleeding, infections Treatment Watchful waiting, targeted therapy, antibodies TKIs (Imatinib, etc.), sometimes transplant Chemotherapy, targeted therapy, immunotherapy Intensive chemo, transplant Curability Usually controlled for years; remission possible Excellent long-term control with TKIs High cure rates, esp. in children Curable with aggressive therapy but relapse risk exists 🌈 Living with CLL: A Message of Reassurance CLL is often called a “chronic” cancer, meaning it can be controlled long-term. Many patients live a normal lifespan, especially with today’s advanced therapies. For many, CLL becomes a condition that is managed like diabetes or hypertension rather than a life-ending disease. Regular follow-up, timely treatment when needed, and support from family and healthcare teams make a huge difference. ❤️ Final Thoughts From Healius Cancer and Haematology Clinics At Healius Cancer and Haematology Clinics, we understand the anxiety that comes with a diagnosis of CLL. The good news is that treatment has advanced tremendously—from chemotherapy to highly effective targeted therapies that give excellent quality of life. Under the guidance of Dr. Mangesh Kamath, our team provides: 👉 Remember: CLL is not the end. With modern science, it is a journey that can be lived with hope, strength, and dignity.

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Breaking Down Chronic Myeloid Leukaemia: Your Guide to Understanding and Beating the Disease

Chronic Myeloid Leukaemia, commonly known as CML, is a type of blood cancer that starts in the bone marrow—the soft tissue inside bones where blood cells are made. CML mainly affects a group of white blood cells called myeloid cells, which normally help fight infections. But in CML, these cells grow uncontrollably and do not function as they should. Global and Indian Prevalence According to the GLOBOCAN 2020 data, leukaemia accounts for over 474,000 new cases and 311,000 deaths globally each year. Among these, CML represents about 15–20% of adult leukaemia cases. In India, CML is the most common adult leukaemia, making up around 30–60% of adult cases depending on the region. It is much rarer in children, but when it occurs, it usually behaves more aggressively than in adults. What Causes CML? CML is not inherited. It happens due to a genetic change in the blood-forming cells. Almost all people with CML have a specific genetic abnormality called the Philadelphia chromosome, which creates a faulty gene called BCR-ABL1. This gene tells the body to produce a protein that makes abnormal cells grow too fast. Risk Factors CML does not usually have clear lifestyle-related risk factors like smoking or diet. However, a few things may slightly increase the risk: It is important to know that for most people, there is no clear reason why they develop CML. Signs and Symptoms In the early (chronic) phase, many people do not feel sick and are diagnosed during routine blood tests. As the disease progresses, symptoms may appear, such as: How is CML Diagnosed? A Complete Blood Count (CBC) is usually the first clue. If the white blood cell count is abnormally high, further tests like bone marrow biopsy, Philadelphia chromosome testing, or BCR-ABL1 gene testing are done to confirm the diagnosis. Phases of CML CML progresses in three phases: Risk Stratification in CML: Why It Matters When someone is diagnosed with CML, doctors do not just look at the blood counts and genes—they also try to estimate how aggressive the disease might be. This process is called risk stratification. What Are the Risk Stratification Scores in CML? Doctors use special scoring systems at the time of diagnosis to estimate how fast the CML may progress. This helps decide the intensity of treatment and monitoring. The most used risk scores include: 🔹 Sokal Score One of the oldest and most widely used tools. It considers: Patients are classified into: 🔹 Hasford Score (Euro Score) An update to the Sokal score, it includes: 🔹 EUTOS Score A simpler model that mainly uses: This score helps predict early response to treatment, especially in patients receiving tyrosine kinase inhibitors (TKIs). 🔹 ELTS Score (EUTOS Long-Term Survival) This newer score focuses on predicting long-term survival, rather than just early response. It includes: It is currently one of the most preferred risk tools for newly diagnosed CML patients. Why Should You Care About These Scores? While the names and numbers may sound technical, these scores help your doctor: Most importantly, they allow your care team to personalize your treatment plan to give you the best possible outcome. Treatment Options Thanks to medical advances, CML is now considered a manageable chronic condition, especially when diagnosed in the chronic phase. 1. Targeted Therapy (TKIs) The mainstay treatment for CML is Tyrosine Kinase Inhibitors (TKIs). These drugs block the BCR-ABL1 protein and stop the cancer from growing. Common TKIs include: Most patients take a TKI as tablets daily, often for life, but some may qualify for treatment-free remission if the disease stays under control for years. 2. Bone Marrow or Stem Cell Transplant This is usually reserved for patients who do not respond to TKIs or are in advanced stages. It is a more intense treatment with potential risks, but it can be curative. 3. Chemotherapy or Immunotherapy Traditional chemotherapy is rarely needed, but interferon-alpha, a type of immunotherapy, was used before TKIs and may still help in selected patients. Newer immunotherapy options are still under research for CML, including CAR T-cell therapy, but are not yet standard treatment. Recent Advances in Treatment Living with CML Can CML Be Prevented? Unfortunately, since the exact cause of CML is unknown in most cases, there are no proven preventive measures. However: can help in early detection and timely treatment. Final Thoughts At Healius Cancer and Haematology Clinics, we understand that a diagnosis of Chronic Myeloid Leukaemia (CML) can be overwhelming—not just for the patient, but for the entire family. But the good news is that CML is one of the most successfully treated forms of leukaemia today. With timely diagnosis, targeted therapies, and close monitoring, it is possible to lead a normal, healthy, and productive life. Under the expert care of Dr. Mangesh Kamath, Medical Oncologist and Haemato-Oncologist, we provide personalized, evidence-based treatment for each patient, including access to the latest in diagnostics, targeted therapy, molecular monitoring, and comprehensive support services. We are committed to walking with you at every step—from diagnosis through treatment and beyond—ensuring that you and your loved ones feel informed, supported, and empowered. If you or someone you know has been diagnosed with CML, remember:You are not alone. You are in trusted hands.

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Acute Myeloid Leukaemia: Understanding the Disease of the Blood

Among the body fluids blood plays a major role in vital functioning of our body. It carries oxygen, nutrients to all organs and acts as a scavenger by carrying waste products to respective organs for further processing where they are removed from the body. The blood consists of four main components which are red blood cells, white blood cells, platelets, and plasma. These components are produced in the bone marrow which is the spongy tissue inside your bones. The myeloid stem cells originated from the bone marrow further differentiates into white blood cells, red cells, and platelets. When there is abnormal or uncontrolled production of these undifferentiated myeloid cells (called myeloblast) cause fast growing cancer of the bone marrow and blood known as Acute Myeloid Leukaemia. What Causes Acute Myeloid Leukaemia (AML)?  AML is caused due to the changes that occur in our genes in the DNA of the Myeloid cells. Yet it is still unknown as to what triggers the change. However, there are few risk factors that increases the risk of AML which includes: How Common Is AML? (Global & Indian Statistics) AML is more common in older adults, with most cases diagnosed after age 65. According to GLOBOCAN 2022 (a global cancer database):   What Are the Symptoms of AML?   Since AML affects blood cell production, symptoms often include:   These symptoms can appear suddenly and worsen quickly, so seeing a doctor early is crucial.   How Do Doctors Determine the Severity of AML? (Risk Stratification) Not all AML cases are the same—some are more aggressive than others. Doctors classify AML into low, intermediate, and high-risk categories based on:   Why Does Risk Stratification Matter? This personalized approach helps doctors choose the best treatment while avoiding unnecessary side effects.   What Are the Treatment Options for AML? 1. Chemotherapy The standard first treatment is “7+3″ chemotherapy—a combination of two drugs given over 7 days. This kills leukaemia cells but also affects healthy cells, causing side effects like hair loss, nausea, and low blood counts.   2. Targeted Therapy  Newer drugs specifically attack cancer cells without harming normal cells as much. Examples include:   3. Stem Cell Transplant For high-risk patients, a bone marrow transplant (from a donor) may be the best chance for a cure. However, it is a complex procedure with risks like infections and graft-versus-host disease (where donor cells attack the body).   4. Supportive Care   Since AML weakens the immune system, patients often need:   5. Special Case: APL (A Highly Curable Subtype)   A rare form of AML called acute promyelocytic leukemia (APL) is treated differently—with vitamin A-based drugs (ATRA) and arsenic trioxide, leading to cure rates above 90%.   Hope for the Future   While AML remains a serious disease, advances in genetic testing, targeted therapies, and immunotherapy are improving survival rates. Early diagnosis and access to specialized care are critical—especially in countries like India, where awareness and healthcare access vary widely.   If you or a loved one experience persistent fatigue, infections, or unusual bleeding, consult a doctor promptly. With the right treatment, many AML patients can achieve remission and lead fulfilling lives.

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